Targets：p38 MAPK inhibitors
medchemexpress products name :ML 00253764 Hydrochloride EW-7197
Product alias :SYN-5200
Description: Non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 0.32, 0.81 and 2.12 μM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.
cas no. : 681847-92-7
Api wt. : N/AReferences PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/17481941