Targets：APC inhibitors
medchemexpress products name :A-839977 Fulvestrant
Product alias :SYN-5005
Description: A-839977 is a potent, CNS penetrating P2X7 antagonist whixh blocks BzATP-evoked calcium influx at P2X7 receptors. (IC50 values are 20nM – human, 42nM -rat and 150nM – mouse). A-839977 displays antinociceptive effects in rat and mice models of inflammatory pain.
cas no. : 870061-27-1
Api wt. : 413.26References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/17475318
Targets：CFTR inhibitors
medchemexpress products name :A-839977 GKT137831
Product alias :SYN-5005
Description: A-839977 is a potent, CNS penetrating P2X7 antagonist whixh blocks BzATP-evoked calcium influx at P2X7 receptors. (IC50 values are 20nM – human, 42nM -rat and 150nM – mouse). A-839977 displays antinociceptive effects in rat and mice models of inflammatory pain.
cas no. : 870061-27-1
Api wt. : 413.26References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/17482179
Targets：FLT3 inhibitors
medchemexpress products name :A-839977 Firategrast
Product alias :SYN-5005
Description: A-839977 is a potent, CNS penetrating P2X7 antagonist whixh blocks BzATP-evoked calcium influx at P2X7 receptors. (IC50 values are 20nM – human, 42nM -rat and 150nM – mouse). A-839977 displays antinociceptive effects in rat and mice models of inflammatory pain.
cas no. : 870061-27-1
Api wt. : 413.26References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/17487421