Tion,germ involved,infection web-site) to predict short and mediumterm mortality. Outcomes: On admission. of sufferers had ! criteria for SIRS. Lung was probably the most widespread infected website (followed by spontaneous bacterial peritonitis ( . of individuals had positive blood culture(s). Probably the most common bacteria have been GN bacillus (GNB) (followed by GP cocci ( Fungal infection was diagnosed in . of sufferers. Higher inICU mortality was predicted by variables related to inflammationinfection,which includes fungal infection (OR, CI: ., p , PPV.),pneumoniainduced acute respiratory failure (OR, CI: ., p , PPV.),sepsisrelated refractory oliguria (OR, CI: ., p , PPV.),sepsisinduced hypotension (OR, CI: p , PPV.),GNB infection (OR, CI: ., p , PPV.),community acquired infection (OR, CI: p ,PPV.),the presence of ! criteria for SIRS (OR, CI: ., p , PPV.),CRP mgdL (OR, CI: , p , PPV.) and leucocytes mm (OR, CI: ., p , PPV.). Most of these parameters greater predicted inICU mortality than a MELD score ! (OR, CI: ., p , PPV.),a Kid Pugh stage C(OR, CI: ., p , PPV.),or possibly a SOFA ! (OR, CI: ., p , PPV.). Among ICU survivors,only nosocomial infection on admission (OR, CI: ., p, PPV.) and admission for septic shock (OR, CI: ., p, PPV.) were related with greater month mortality. Conclusion: In critically ill cirrhotics,some parameters associated with SIRS and infection are able to superior predict shortterm mortality than prognostic scores. A history of septic shock is actually a robust predictor of month mortality,even following the manage of organ failures enabling ICU discharge,and may perhaps develop into an indication for secondary antibioprophylaxis andor liver transplantation. Nosocomial infection also have sustained impact on mortality. Disclosure of Interest: None declaredUnited European Gastroenterology Journal (S) hours following the procedure,no further complications occurred. In the following year,patients had episodes of variceal hemorrhage (on typical about months after the elective process. Six of them eventually died ( Variceal bleeding recurrence was significantly less common in patients that MedChemExpress GW274150 underwent less frequent procedures ( weeks). Conclusion: Esophageal varices band ligation is an powerful method to stop both inaugural and recurrent episodes of bleeding. Thabut,M. Mallet,S. Tripon,M. Rudler,N. Weiss,on behalf of Brain Liver PitieSalpetriere Study Group (BLIPS) Hepatological ICU,NeuroICU,La PitieSalpetriere Hospital,Assistance Publique Hopitaux de Paris,PARIS,France Contact E-mail Address: dthabutgmail Introduction: Near Infrared Spectroscopy (NIRS) is really a noninvasive optical method permitting a continuous measurement of brains hemoglobin saturation in oxygen (rSO). It’s regarded as as a surrogate marker of cerebral insult,and recognized as a useful tool in in cardiovascular surgery and neuromonitoring. A rSO is linked with elevated neurological impairment and postoperative mortality. In cirrhotic sufferers with gastrointestinal bleeding (GIB),hemoglobin (Hb) threshold for transfusion has been not too long ago lowered to gdL. Some patients create hepatic encephalopathy (HE) following GIB. In subarachnoid hemorrhage,a threshold of gdL PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/19389808 of Hb could worsen neurological outcome. Aims Solutions: The aim of this study was to assess brain oxygenation using NIRS in cirrhotic individuals with acute GIB admitted to ICU and managed based on recent guidelines,and to establish if brain injury was related with Hb levels. Cirrhotic sufferers admitted in ICU for acute GIB were prospectively incorporated. Bilateral continuo.