Es readily available instruments to enhance visualization of cutting lines. Our TTSPS method is often universally applied to standard ESD. Disclosure of Interest: None declaredP CAPNOGRAPHY For the duration of SEDATION FOR ENDOSCOPIC Therapy Working with CARBON DIOXIDE Supply Method H. Takamaru,Y. Kawaguchi,I. Oda,M. Sekiguchi,S. Abe,S. Nonaka,H. Suzuki,S. Yoshinaga,Y. Saito Endoscopy Division,Anesthesiology and Crucial Care Medicine,National Cancer Center Hospital,Tokyo,Japan Speak to E-mail Address: h.takamarugmail Introduction: A respiratory monitoring throughout sedation for endoscopy has a crucial function. Pulse oximetry is among the most common strategies for respiratory monitoring,even so,unexpected adverse effect may well take place with pulse oximetry only. Within the situations of deep sedation,visual examination,auscultation and monitoring by capnography can be advised. On the other hand,only few research reported regarding the capnography in the course of sedation for endoscopic treatment of lesions positioned in upper gastrointestinal tract using endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) method,with deep sedation and carbon dioxide provide method. Aims Approaches: The aim of this study is always to evaluate the stability of respiratory monitoring by capnography in the course of deep sedation for ESDEMR applying carbon dioxide provide program. Twentysix individuals with effectively monitored each capnography and respiratory monitoring method by breath sounds (Rad Masimo,Japan) amongst consecutive patients who underwent endoscopic treatment (ESDEMR) under deep sedation without having intubation by anesthesiologist from December to October had been analyzed. Oxygen saturation (SpO) was IQ-1S (free acid) measured by pulse oximetry. Respiratory price per minute (RR) was measured by side stream capnography and recorded every seconds. RR was also measured from breath sounds by Radas gold standard and recorded each seconds. We compared the typical value of RR for every seconds with RR by capnography and calculated Pearson’s correlation coefficient. We also defined “outlier” when the value of RR by capnography was additional or less than RR range of by Rad Outcomes: In this study,of sufferers have been male and median age was . years old (IQR: ..). Imply BMI was .. Sufferers who had cardiovascular or pulmonary illness have been . and . ,respectively. Place exactly where patients had the lesions was follows; individuals have lesions in esophagus,individuals in PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28550243 standard stomach,sufferers in gastric tube,one particular patient in gastric remnant. Imply size from the resected specimens was .mm mm). Median time of process is minutes (IQR: . . min). Anesthesiologist employed fentanyl and propofol for all patients. Imply volume of total administered agent is .mg and mg,respectively. The average of SpO,RR by Radand RR by capnography for the duration of process was . .min and respectively. Four instances showed transient hypoxia (SpO . Among 4 circumstances showed hypoxemia for couple of minute,and this adverse impact could possibly be detected by capnography as apnea prior to pulse oximetry detection. One particular case showed comparatively sturdy correlation (r.),and 3 circumstances showed weak correlation r),whilst other circumstances showed no correlation involving RR measured by capnography and by Rad Median frequency of outlier for RR by capnograhpy was . (IQR: . Conclusion: Respiratory monitoring by capnography through deep sedation for endoscopic treatment with carbon dioxide supply program may very well be unstable and want some improvement in some scenario. Disclosure of Interest: None declaredP Development OF A NOVEL ENDOSCOPIC SUTURING.