Name: Human Ephrin B Receptor 1/EphB1 (C-Fc)
Synonyms: Ephrin Type-B Receptor 1;ELK;EPH Tyrosine Kinase 2;EPH-Like Kinase 6;EK6;hEK6;Neuronally-Expressed EPH;Related Tyrosine Kinase;NET;Tyrosine-Protein Kinase Receptor EPH-2;EphB1;ELK;EPHT2;HEK6
Expression host: HEK293 Cells
Sequence: Met18-Pro540
Accesstion: P54762
Species: Human
Mol_Mass: 85.6 kDa
AP_Mol_Mass: 85-110 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the print
Reconstitution: Please refer to the printed manual for detailed information.
Background: Ephrin Type-B Receptor 1 (EphB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EphB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EphB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EphB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
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