Name: Human Ephrin-A1/EFNA1 Recombinant Protein (Fc Tag)
Synonyms: Ephrin-A1;EPH-Related Receptor Tyrosine Kinase Ligand 1;LERK-1;Immediate Early Response Protein B61;Tumor Necrosis Factor Alpha-Induced Protein 4;TNF Alpha-Induced Protein 4;EFNA1;EPLG1;LERK1;TNFAIP4
Expression host: HEK293 Cells
Sequence: Asp19-Ser182
Accesstion: AAH32698.1
Species: Human
Mol_Mass: 46.5 kDa
AP_Mol_Mass: 55-60 kDa
Tag: C-Fc
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
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