Name: Human EphA7/EHK3 Recombinant Protein (His Tag)
Synonyms: Ephrin Type-A Receptor 7;EPH Homology Kinase 3;EHK-3;EPH-Like Kinase 11;EK11;hEK11;EphA7;EHK3;HEK11
Expression host: HEK293 Cells
Sequence: Gln28-Ile556
Accesstion: Q15375
Species: Human
Mol_Mass: 60.2 kDa
AP_Mol_Mass: 72 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed man
Reconstitution: Please refer to the printed manual for detailed information.
Background: Ephrin Type-A Receptor 7 (EphA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EphA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EphA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EphA7 is expressed at a substantial level in most human lung cancers. The high expression of EphA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EphA7 may involve in smoking related lung carcinogenesis.
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