Name: Rhesus macaque CD47/IAP Recombinant Protein (Fc Tag)
Synonyms: Leukocyte Surface Antigen CD47;Antigenic Surface Determinant Protein OA3;Integrin-Associated Protein;IAP;Protein MER6;CD47;MER6
Expression host: HEK293 Cells
Sequence: Gln19-Pro139
Accesstion: F7A802
Species: Rhesus macaque
Mol_Mass: 40.8 kDa
AP_Mol_Mass: 60-90 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the
Reconstitution: Please refer to the printed manual for detailed information.
Background: CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
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