Name: Mouse TROP2/TACSTD2 Recombinant Protein (His Tag)
Synonyms: Tumor-associated calcium signal transducer 2;Tacstd2;Trop2;Cell surface glycoprotein TROP-2;TROP-2;C80403;EGP-1;GA733-1;Ly97
Expression host: HEK293 Cells
Sequence: Gln25-Gly270
Accesstion: Q8BGV3
Species: Mouse
Mol_Mass: 28.8 kDa
AP_Mol_Mass: 38-55 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein TROP-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
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