Name: Mouse ST6GALNAC2 Recombinant Protein (His Tag)
Synonyms: Gal-beta-1;3-GalNAc alpha-2;6-sialyltransferase;GalNAc alpha-2;6-sialyltransferase II;ST6GalNAc II;Sialyltransferase 7B;SIAT7-B;II;Siat7;Siat7b;ST6GalNAc
Expression host: HEK293 Cells
Sequence: Ser28-Arg373
Accesstion: P70277
Species: Mouse
Mol_Mass: 40.4 kDa
AP_Mol_Mass: 45 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 50mMTris,150mMNaCl,pH7.5.
Reconstitution: Not Applicable
Background: Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type?II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.?it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
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