Name: Mouse SerpinF2/SERPINF2 Recombinant Protein (Fc Tag)
Synonyms: Alpha-2-antiplasmin;Alpha-2-AP;Alpha-2-plasmin inhibitor;Alpha-2-PI;Serpin F2;Serpinf2
Expression host: HEK293 Cells
Sequence: Val28-Lys491
Accesstion: Q61247
Species: Mouse
Mol_Mass: 79.3 kDa
AP_Mol_Mass: 90-120 kDa
Tag: C-Fc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.
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