Name: Human Zic3 Recombinant Protein (His tag)
Synonyms: Zinc finger protein ZIC 3;ZIC3;Zinc finger protein 203;Zinc finger protein of the cerebellum 3
Expression host: E.coli
Sequence: Met 1-Val467
Accesstion: O60481
Species: Human
Mol_Mass: 51.3 kDa
AP_Mol_Mass: 52 kDa
Tag: N-His & C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from sterile PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: ZIC3 (zinc-finger protein of the cerebellum 3) is a 50 kDa (predicted) member of the GLI C2H2-type Zn-finger protein family. It is expressed in cerebellum, and apparently plays a key role in left-right body axis formation. Human ZIC3 is 467 amino acids (aa) in length. It contains N?terminal poly-Ala (aa 46?55) and poly-His (aa 87?97) segments, followed by five C2H2-type Zn-fingers (aa 253?410). Within the zinc finger region, there is an overlapping NES (aa 290?349) and two NLS’s (aa 367?382 and 403?410). ZIC3 reportedly binds to GLI-3.
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