Name: Human UBE2B/HR6B Recombinant Protein

Synonyms: Ubiquitin-Conjugating Enzyme E2 B;RAD6 Homolog B;HR6B;hHR6B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;UBE2B;RAD6B

Expression host: E.coli

Sequence: Met 1-Ser152

Accesstion: P63146

Species: Human

Mol_Mass: 17.5 kDa

AP_Mol_Mass: 18 kDa

Tag: None

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.

Reconstitution: Not Applicable

Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

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