Name: Human Arginase-1/ARG1 Recombinant Protein (E.coli, His Tag)

Synonyms: Arginase-1;Liver-type arginase;Type I arginase;ARG1

Expression host: E.coli

Sequence: Met 1-lys322

Accesstion: P05089

Species: Human

Mol_Mass: 35.8 kDa

AP_Mol_Mass: 40 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 7.4.

Reconstitution: Not Applicable

Background: ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.

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