Name: Human ST6GAL1 Recombinant Protein (His Tag)
Synonyms: Beta-Galactoside Alpha-2;6-Sialyltransferase 1;Alpha 2;6-ST 1;B-Cell Antigen CD75;CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2;6-Sialyltransferase 1;ST6Gal I;ST6GalI;Sialyltransferase 1;ST6GAL1;SIAT1
Expression host: HEK293 Cells
Sequence: Lys27-Cys406
Accesstion: P15907
Species: Human
Mol_Mass: 44.6 kDa
AP_Mol_Mass: 41-60 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: The ST6GAL1 gene encodes β-Galactosamide α-2;6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2;6-sialylation of Galβ1;4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
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