Name: Human SEMA4B Recombinant Protein (His Tag)
Synonyms: Semaphorin-4B;KIAA1745;SEMAC and SEMA4B
Expression host: HEK293 Cells
Sequence: Leu39-Glu712
Accesstion: Q9NPR2
Species: Human
Mol_Mass: 75.7 kDa
AP_Mol_Mass: 86 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution: Not Applicable
Background: The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
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