Name: Human POLD2 Recombinant Protein (His Tag)

Synonyms: DNA Polymerase Delta Subunit 2;DNA Polymerase Delta Subunit p50;POLD2

Expression host: E.coli

Sequence: Met 1-Pro469

Accesstion: P49005

Species: Human

Mol_Mass: 52.3 kDa

AP_Mol_Mass: 56 kDa

Tag: C-His

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Reconstitution: Not Applicable

Background: DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3′ to 5′ exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).

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