Name: Human Placental Alkaline Phosphatase 1/ALPP Recombinant Protein (His Tag)

Synonyms: Alkaline Phosphatase;placental type;Alkaline Phosphatase Regan isozyme;Placental Alkaline Phosphatase 1;ALPP and PLAP;

Expression host: HEK293 Cells

Sequence: Ile23-Asp506

Accesstion: P05187

Species: Human

Mol_Mass: 53.7 kDa

AP_Mol_Mass: 60-85 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.2mM CaCl2, 10% Glycerol, pH 7.5.

Reconstitution: Not Applicable

Background: ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer’s research.

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