Name: Human KLF6 Recombinant Protein
Synonyms: Krueppel-Like Factor 6;B-Cell-Derived Protein 1;Core Promoter Element-Binding Protein;GC-Rich Sites-Binding Factor GBF;Proto-Oncogene BCD1;Suppressor of Tumorigenicity 12 Protein;Transcription Factor Zf9;KLF6;BCD1;COPEB;CPBP;ST12
Expression host: E.coli
Sequence: Met 1-Ser109
Accesstion: Q99612-3
Species: Human
Mol_Mass: 12.6 kDa
AP_Mol_Mass: 13-19 kDa
Tag: None
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
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