Name: Human Fas Ligand / TNFSF6 (N-6His)
Synonyms: apoptosis (APO-1) antigen ligand 1;Apoptosis antigen ligand;APT1LG1CD95L;APTL;CD178 antigen;CD178;CD95L;CD95-L;Fas antigen ligand;Fas ligand (TNF superfamily;member 6);Fas Ligand;FASLCD95 ligand;FASLG;TNFSF6
Expression host: HEK293 Cells
Sequence: Pro134-Leu281
Accesstion: P48023
Species: Human
Mol_Mass: 17.7 kDa
AP_Mol_Mass: 20-30 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Not Applicable
Background: Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
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