Product Name :
Mutant IDH1-IN-4
Description:
Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.
CAS:
1416270-18-2
Molecular Weight:
438.56
Formula:
C25H34N4O3
Chemical Name:
8-cyclopropyl-6-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-3,3-dimethyl-1H,3H,4H-pyrano[3,4-c]pyridine-5-carbonitrile
Smiles :
COCCC(=O)N1CCN(C[C@H]1C1CC1)C1N=C(C2CC2)C2COC(C)(C)CC=2C=1C#N
InChiKey:
GNDMXEAGAZOBEM-NRFANRHFSA-N
InChi :
InChI=1S/C25H34N4O3/c1-25(2)12-18-19(13-26)24(27-23(17-6-7-17)20(18)15-32-25)28-9-10-29(22(30)8-11-31-3)21(14-28)16-4-5-16/h16-17,21H,4-12,14-15H2,1-3H3/t21-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.Tofacitinib medchemexpress
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Doxycycline manufacturer
Additional information:
Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.|Product information|CAS Number: 1416270-18-2|Molecular Weight: 438.56|Formula: C25H34N4O3|Chemical Name: 8-cyclopropyl-6-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-3,3-dimethyl-1H,3H,4H-pyrano[3,4-c]pyridine-5-carbonitrile|Smiles: COCCC(=O)N1CCN(C[C@H]1C1CC1)C1N=C(C2CC2)C2COC(C)(C)CC=2C=1C#N|InChiKey: GNDMXEAGAZOBEM-NRFANRHFSA-N|InChi: InChI=1S/C25H34N4O3/c1-25(2)12-18-19(13-26)24(27-23(17-6-7-17)20(18)15-32-25)28-9-10-29(22(30)8-11-31-3)21(14-28)16-4-5-16/h16-17,21H,4-12,14-15H2,1-3H3/t21-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32809492 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|