Name: Human ERP57/PDIA3 Recombinant Protein (His Tag)
Synonyms: PDIA3 protein;Protein disulfide-isomerase A3;58 kDa glucose-regulated protein;Disulfide isomerase ER-60;ER protein 57
Expression host: HEK293 Cells
Sequence: Ser25-Leu505
Accesstion: P30101
Species: Human
Mol_Mass: 55.3 kDa
AP_Mol_Mass: 60 kDa
Tag: C-His
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
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