Name: Human EphB2 Recombinant Protein (Fc Tag)

Synonyms: CAPB;DRT;EK5;EPHT3;ERK;Hek5;PCBC;Tyro5;EphB2;Ephrin type-B receptor 2

Expression host: HEK293 Cells

Sequence: Val19-Ser482

Accesstion: Q6NVW1

Species: Human

Mol_Mass: 78.5 kDa

AP_Mol_Mass: 95-120 kDa

Tag: C-Fc

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Ephrin type-B receptor 2(EphB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EphB2 contains 1 Eph LBD domain; 2 fibronectin type-III domains; 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands; the ephrins; mediate numerous developmental processes; particularly in the nervous system. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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