Name: Human CD48 Recombinant Protein (mFc Tag)
Synonyms: CD48 antigen;B-lymphocyte activation marker BLAST-1;BCM1 surface antigen;Leukocyte antigen MEM-102;TCT.1;CD48;BCM1;BLAST1;hCD48;mCD48;SLAMF2
Expression host: HEK293 Cells
Sequence: Gln27-Ser220
Accesstion: P09326
Species: Human
Mol_Mass: 48.9 kDa
AP_Mol_Mass: 60-80 kDa
Tag: C-mFc
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150mM NaCl, pH 8.0.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the prin
Reconstitution: Please refer to the printed manual for detailed information.
Background: CD48 antigen; also known as B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48; BCM1;and BLAST1; CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain; but does not have a transmembrane domain; however; but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.
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