Name: Cynomolgus FGL1 (C-Avi-6His) Biotinylated

Synonyms: Fibrinogen-like protein 1;FGL1;HP-041;Hepassocin;HFREP-1;LFIRE-1

Expression host: HEK293 Cells

Sequence: Leu23-Ile312

Accesstion: A0A2K5X990

Species: Cynomolgus macaques

Mol_Mass: 34.8 kDa

AP_Mol_Mass: 36 kDa

Tag: C-Avi-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.

Reconstitution: Not Applicable

Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

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