Name: Human CCL1/I-309 Recombinant Protein
Synonyms: C-C Motif Chemokine 1;Small-Inducible Cytokine A1;T Lymphocyte-Secreted Protein I-309;CCL1;SCYA1
Expression host: E.coli
Sequence: Lys24-Lys96
Accesstion: P22362
Species: Human
Mol_Mass: 8.6 kDa
AP_Mol_Mass: 10 kDa
Tag: None
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play acentral role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be ahomologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequenceidentity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surfacechemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cellfusion and virus infection.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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