Name: Human Cathepsin L2/CTSL2 Recombinant Protein (His Tag)
Synonyms: Cathepsin L2;Cathepsin U;Cathepsin V;CTSL2;CATL2;CTSU;CTSV
Expression host: HEK293 Cells
Sequence: Val18-Val334
Accesstion: O60911
Species: Human
Mol_Mass: 36.7 kDa
AP_Mol_Mass: 33-43 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, pH5.5.
Reconstitution: Not Applicable
Background: Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.
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