Name: Human Carboxypeptidase B1/CPB1 Recombinant Protein (His Tag)

Synonyms: Carboxypeptidase B;Pancreas-Specific Protein;PASP;CPB1;CPB;PCPB

Expression host: HEK293 Cells

Sequence: His16-Tyr417

Accesstion: P15086

Species: Human

Mol_Mass: 46.9 kDa

AP_Mol_Mass: 47 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Reconstitution: Not Applicable

Background: Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.

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