Name: Human Carbonic Anhydrase 5B/CA5B Recombinant Protein (His Tag)
Synonyms: Carbonic Anhydrase 5B Mitochondrial;Carbonate Dehydratase VB;Carbonic Anhydrase VB;CA-VB;CA5B
Expression host: E.coli
Sequence: Cys34-Pro317
Accesstion: Q9Y2D0
Species: Human
Mol_Mass: 33.8 kDa
AP_Mol_Mass: 33 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Carbonic Anhydrase 5B (CA5B) is a member of alpha-Carbonic Anhydrase family (CAs) that catalyze the reversible hydration of carbon dioxide. CAs is associated with many biological processes; including calcification; respiration; bone resorption; acid-base balance and the formation of aqueous humor. CA5B is highly expressed in heart; pancreas; kidney; placenta; lung; and skeletal muscle; but it is restricted to the liver. CA5B is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA; CA-VA. CA5B is inhibited by coumarins; sulfonamide derivatives such as acetazolamide (AZA); saccharin; and Foscarnet.
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