Name: Human Carbonic Anhydrase 1/CA1 Recombinant Protein (His Tag)
Synonyms: Carbonic Anhydrase 1;Carbonate Dehydratase I;Carbonic Anhydrase B;CAB;Carbonic Anhydrase I;CA-I;CA1
Expression host: E.coli
Sequence: Ala2-Phe261
Accesstion: P00915
Species: Human
Mol_Mass: 29.9 kDa
AP_Mol_Mass: 25-35 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 12.5mM Tris-HCl, 75mM NaCl, pH 7.5.
Reconstitution: Not Applicable
Background: Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.
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