Name: Human C1qBP Recombinant Protein (aa 74-282, His Tag)
Synonyms: Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial;ASF/SF2-Associated Protein p32;Glycoprotein gC1qBP;C1qBP;Hyaluronan-Binding Protein 1;Mitochondrial Matrix Protein p32;gC1q-R Protein;p33;C1qBP;GC1qBP;HABP1;SF2P32;gC1qR
Expression host: E.coli
Sequence: Leu74-Gln282
Accesstion: Q07021
Species: Human
Mol_Mass: 24.9 kDa
AP_Mol_Mass: 34 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 1mM DTT, pH 7.5.
Reconstitution: Not Applicable
Background: Complement Component 1Q Subcomponent-Binding Protein (C1qBP) is a nucleus protein that belongs to the MAM33 family. C1qBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1qBP is a critical mediator of p14ARF-induced apoptosis. C1qBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1qBP and cC1qR/CR. C1qBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
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