Name: Mouse S100a9 Recombinant Protein (His Tag)
Synonyms: Leukocyte L1 complex heavy chain;60B8AG;CAGB;Calgranulin B;Calgranulin-B;Calprotectin L1H subunit;CFAG;CGLB;Cystic fibrosis antigen B;L1AG;Leukocyte L1 complex heavy chain;LIAG;MAC387;MIF;Migration inhibitory factor related protein 14;Migration inhibitory factor-related protein 14;MRP 14;MRP-14;MRP14;Myeloid-related protein 14;NIF;OTTHUMP00000015331;p14;Protein S100-A9;S100 A9;S100 calcium binding protein A9;S100 calcium binding protein A9 calgranulin B;S100 calcium-binding protein A9;S100A9;S10A9
Expression host: E.coli
Sequence: Ala2-Lys113
Accesstion: P31725
Species: Mouse
Mol_Mass: 14.3 kDa
AP_Mol_Mass: 15-18 kDa
Tag: N-His & C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from sterile PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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