Name: Mouse MMP12/MMP-12/HME Recombinant Protein (His Tag)

Synonyms: Macrophage metalloelastase;MME;Matrix metalloproteinase-12;MMP-12;Mmp12;Mme;Mmel

Expression host: HEK293 Cells

Sequence: Ala29-Cys473

Accesstion: P34960

Species: Mouse

Mol_Mass: 53.0 kDa

AP_Mol_Mass: 64 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl,0.01%Tween80, 1mM EDTA, 50% Glycerol, pH6.0.

Reconstitution: Not Applicable

Background: Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1′ site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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