Name: Mouse FSTL1 Recombinant Protein (His Tag)
Synonyms: Follistatin-related protein 1;Follistatin-like protein 1;TGF-beta-inducible protein TSC-36;Fstl1
Expression host: HEK293 Cells
Sequence: Glu19-Ile306
Accesstion: Q62356
Species: Mouse
Mol_Mass: 33.5 kDa
AP_Mol_Mass: 45-58 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the Follistatin family of proteins. FSTL1 is composed of a Follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGFβ1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.
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