Name: Mouse Carbonic Anhydrase 4/CA4 Recombinant Protein (aa 17-420, His Tag)
Synonyms: CA4;CAIV;CA-IV;Car4;Carbonate dehydratase IV;Carbonic Anhydrase 4;Carbonic Anhydrase IVRP17;carbonic dehydratase IV;EC4.2.1.1;retinitis pigmentosa 17;RP17
Expression host: HEK293 Cells
Sequence: Gly17-Tyr420
Accesstion: Q6P8K8
Species: Mouse
Mol_Mass: 46.7 kDa
AP_Mol_Mass: 50 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Carboxypeptidase A4 (CPA4) is a member of the peptidase M14 family. CPA4 is metalloprotease that could be involved in the histone hyperacetylation pathway. CPA4 binds one zinc ion per subunit and could catalyze to release of a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val.They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as carboxypeptidase Xs, have lost their catalytic activity. Carboxypeptidases play important roles in digestion of food, processing of bioactive peptides and blood coagulation.
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