Name: Mouse Alpha-1-antitrypsin 1-1/Serpin A1e (C-6His)
Synonyms: Alpha-1-antitrypsin 1-5;Alpha-1 protease inhibitor 5;Serine protease inhibitor 1-5;Serine protease inhibitor A1e;Serpin A1e;Serpina1e;Dom5;Spi1-5
Expression host: HEK293 Cells
Sequence: Glu25-Lys413
Accesstion: Q00898
Species: Mouse
Mol_Mass: 44.5 kDa
AP_Mol_Mass: 47-68 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.
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