Name: Human XPNPEP3 Recombinant Protein (His Tag)
Synonyms: Probable Xaa-Pro Aminopeptidase 3;X-Pro Aminopeptidase 3;Aminopeptidase P3;APP3;XPNPEP3
Expression host: E.coli
Sequence: Met 1-Ser507
Accesstion: Q9NQH7
Species: Human
Mol_Mass: 60.2 kDa
AP_Mol_Mass: 65 kDa
Tag: N-His & C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.
Reconstitution: Not Applicable
Background: Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
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