Name: Human XPNPEP2 Recombinant Protein (His Tag)

Synonyms: Xaa-Pro Aminopeptidase 2;Aminoacylproline Aminopeptidase;Membrane-Bound Aminopeptidase P;Membrane-Bound APP;Membrane-Bound AmP;mAmP;X-Pro Aminopeptidase 2;XPNPEP2

Expression host: HEK293 Cells

Sequence: His22-Ala650

Accesstion: O43895

Species: Human

Mol_Mass: 71.6 kDa

AP_Mol_Mass: 78 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Background: Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesn’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.

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