Name: Human XIAP Recombinant Protein (His tag)
Synonyms: E3 ubiquitin-protein ligase XIAP;XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;Inhibitor of apoptosis protein 3;RING-type E3 ubiquitin transferase XIAP;X-linked inhibitor of apoptosis protein
Expression host: E.coli
Sequence: Met 1-Ser 497
Accesstion: P98170
Species: Human
Mol_Mass: 54.6 kDa
AP_Mol_Mass: 54 kDa
Tag: N-His & C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from sterile PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: XIAP (X-chromosome linked inhibitor of apoptosis) is a member of the apoptosis (IAP) family of proteins that inhibit caspases. The BIR2 domain of XIAP inhibits caspase-3 and caspase-7. The ability of XIAP to inhibit caspases is prevented by SMAC/Diablo through binding to XIAP-BIR2 and -BIR3 domains.
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