Name: Human VCP Recombinant Protein (His Tag)
Synonyms: Transitional Endoplasmic Reticulum ATPase;TER ATPase;15S Mg(2+)-ATPase p97 Subunit;Valosin-Containing Protein;VCP
Expression host: E.coli
Sequence: Ala2-Asn589
Accesstion: P55072
Species: Human
Mol_Mass: 66.3 kDa
AP_Mol_Mass: 75 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, pH8.0.
Reconstitution: Not Applicable
Background: Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.
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