Name: Human UBE2B/HR6B Recombinant Protein (His Tag)
Synonyms: Ubiquitin-Conjugating Enzyme E2 B;RAD6 Homolog B;HR6B;hHR6B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;UBE2B;RAD6B
Expression host: HEK293 Cells
Sequence: Met 1-Ser152
Accesstion: P63146
Species: Human
Mol_Mass: 18.3 kDa
AP_Mol_Mass: 17 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution: Not Applicable
Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18; UBR2; and WAC. UBE2B is required for post-replicative DNA damage repair. Additional; UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
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