Name: Human TSTA3/SDR4E1 Recombinant Protein (His Tag)
Synonyms: GDP-L-Fucose Synthase;GDP-4-Keto-6-Deoxy-D-Mannose-3;5-Epimerase-4-Reductase;Protein FX;Red Cell NADP(H)-Binding Protein;Short-Chain Dehydrogenase/Reductase Family 4E Member 1;TSTA3;SDR4E1
Expression host: E.coli
Sequence: Met 1-Lys321
Accesstion: Q13630
Species: Human
Mol_Mass: 37.0 kDa
AP_Mol_Mass: 40 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
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