Name: Human ASB13 Recombinant Protein (His Tag)

Synonyms: Ankyrin repeat and SOCS box protein 13;ASB13;

Expression host: E.coli

Sequence: Met 1-Asn278

Accesstion: Q8WXK3

Species: Human

Mol_Mass: 31.4 kDa

AP_Mol_Mass: 28 kDa

Tag: N-His

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 4M Urea, pH 7.4.

Reconstitution: Not Applicable

Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

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