Name: Human SUMF1 Recombinant Protein (His Tag)
Synonyms: Sulfatase-Modifying Factor 1;C-Alpha-Formylglycine-Generating Enzyme 1;SUMF1;FGE
Expression host: HEK293 Cells
Sequence: Ser34-Asp374
Accesstion: Q8NBK3
Species: Human
Mol_Mass: 38.4 kDa
AP_Mol_Mass: 38-42 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.
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