Name: Human ST8SIA1 Recombinant Protein (His Tag)
Synonyms: Alpha-N-Acetylneuraminide Alpha-2;8-Sialyltransferase;Alpha-2;8-Sialyltransferase 8A;Ganglioside GD3 Synthase;Ganglioside GT3 Synthase;Sialyltransferase 8A;SIAT8-A;Sialytransferase St8Sia I;ST8SiaI;ST8SIA1;SIAT8;SIAT8A
Expression host: HEK293 Cells
Sequence: Tyr49-Ser356
Accesstion: Q92185
Species: Human
Mol_Mass: 36.2 kDa
AP_Mol_Mass: 48 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: α-N-Acetylneuraminide α-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.
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