Name: Human ApolipoRecombinant Protein C-II/APOC2 Recombinant Protein (His Tag)
Synonyms: Apolipoprotein C-II;Apolipoprotein C2;APC2 and APOC2
Expression host: E.coli
Sequence: Thr23-Glu101
Accesstion: AAP35354.1
Species: Human
Mol_Mass: 10.0 kDa
AP_Mol_Mass: 14 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
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