Name: Human SerpinH1/SERPINH1 Recombinant Protein (His Tag)
Synonyms: Serpin H1;47 kDa Heat Shock Protein;Arsenic-Transactivated Protein 3;AsTP3;Cell Proliferation-Inducing Gene 14 Protein;Collagen-Binding Protein;Colligin;Rheumatoid Arthritis-Related Antigen RA-A47;SERPINH1;CBP1;CBP2;HSP47;SERPINH2
Expression host: HEK293 Cells
Sequence: Ala19-Leu418
Accesstion: P50454
Species: Human
Mol_Mass: 45.5 kDa
AP_Mol_Mass: 51 kDa
Tag: C-His
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
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