Name: Human SEPHS1 Recombinant Protein (His Tag)
Synonyms: Selenide;water dikinase 1;Selenium donor protein 1;Selenophosphate synthase 1;SEPHS1;SELD;SPS;SPS1
Expression host: HEK293 Cells
Sequence: Met 1-Ser392
Accesstion: P49903
Species: Human
Mol_Mass: 43.9 kDa
AP_Mol_Mass: 42 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 100mM glycine, 10% Glycerol, pH 7.3.
Reconstitution: Not Applicable
Background: Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.
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