Name: Human APN Recombinant Protein (His Tag)

Synonyms: Aminopeptidase N;ANPEP;AP-M;APN;AP-N;CD13 antigen;CD13;CD13APN;PEPN;PEPNhAPN

Expression host: HEK293 Cells

Sequence: Lys69-Lys967

Accesstion: P15144

Species: Human

Mol_Mass: 103.5 kDa

AP_Mol_Mass: 110-130 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

Reconstitution: Not Applicable

Background: ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.

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