Name: Human Reticulocalbin 3/RCN3 Recombinant Protein (aa 21-328, His Tag)

Synonyms: Reticulocalbin-3;EF-Hand Calcium-Binding Protein RLP49;RCN3

Expression host: HEK293 Cells

Sequence: Lys21-Leu328

Accesstion: Q96D15

Species: Human

Mol_Mass: 36.2 kDa

AP_Mol_Mass: 43 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 10% Glycerol, pH 7.4.

Reconstitution: Not Applicable

Background: Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition; it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.

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